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Irritable Bowel Syndrome:  How To Get Your Life Back What is IBS? Most people reading this know at least one person with this common condition—at any given time, 10 to 20 percent of a population may have IBS. Irritable bowel syndrome (IBS) is known by a variety of other terms: spastic colon, spastic colitis, mucous colitis, and nervous or functional bowel. Usually, it is a disorder of the large intestine (colon), although other parts of the intestinal tract even up to the stomach can be affected.